1. Protein is an organic compound consisting of carbon, hydrogen, oxygen, nitrogen and sometimes sulphur and phosphorus.
2. Protein is a natural polymer, the monomer of protein is amino acid.
3. The basic structure of amino acid:
Basic structure of amino acid |
4. Amino acid has a basic amino group, -NH2 and a acidic carboxyl group, -COOH and a side chain, R. There are 20 types of amino acids found in proteins. Different amino acids have different R chain.
Amino Acids |
Three Letter Abbreviation
|
Alanine |
Ala
|
Arginine |
Arg
|
Asparagine |
Asn
|
Aspartic acid |
Asp
|
Cysteine |
Cys
|
Glutamine |
Gln
|
Glutamic acid |
Glu
|
Glycine |
Gly
|
Histidine |
His
|
Isoleucine |
Ile
|
Leucine |
Leu
|
Lysine |
Lys
|
Methionine |
Met
|
Phenylalanine |
Phe
|
Proline |
Pro
|
Serine |
Ser
|
Threonine |
Thr
|
Tryptophan |
Trp
|
Tyrosine |
Tyr
|
Valine |
Val
|
5. Amino acids can be classified into 4 major types based on the side chain (R).
- Non-polar amino acids
- Polar amino acids
- Basic amino acids
- Acidic amino acids
Non-polar amino acids
- Non-polar amino acids are amino acids with a non-polar side chain.
- Examples: glycine, alanine, valine, leucine, methionine, isoleucine, phenylalanine, and tryptophan.
Non-polar amino acids |
Polar amino acids
- Polar amino acids are amino acids with a polar side group.
- Examples: serine, threonine, asparagine, glutamine, tyrosine, and cysteine.
Polar amino acids
Basic amino acids
- Basic amino acids have side chain which is an amino group, NH2, a base group.
- Examples: lysine, arginine, and histidine.
Basic amino acids |
Acidic amino acids
- Acidic amino acids have a side chain which is a carboxylic group, COOH.
- Examples: aspartic acid and glutamic acid.
Acidic amino acids |
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